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Nonlinear endoscopy

 

3D rendered image animation of rat esophageal tissue stained with acridine orange in situ as captured with a nonlinear endoscope. Second harmonic generation image (red) overlaid onto a fluorescence image (green). Image made in conjunction with Dr Ling Fu (formerly Swinburne University of Technology)

 

Fu L., Jain A., Xie H., Cranfield C., and  Gu M., (2006). Nonlinear optical endoscopy based on a double clad photonic crystal fiber and a MEMS mirror. Optics Express 14: 1027-1032.

 

 Fu L, Jain A, Cranfield C, Xie H, and Gu M (2007). Three-dimensional nonlinear optical endoscopy. J. Biomed. Opt. 12: 040501.