Y-DNA Project


Index


Background Information

The human body has 100 million million cells. A cell is the basic unit of structure in living things. Chromosomes are tiny bodies in a cell which carry the genes. A gene is a piece of DNA (deoxyribonucleic acid) which carries the hereditary information.

Only males have the Y-Chromosome which is passed from father to son usually in identical form from one generation to the next. Occasionally, a change (which is called a mutation) occurs between a father and son. Some families have more changes than others. As surnames are passed from father to son through the generations, Y-DNA testing is confined to men with the same surname (or phonetically similar surnames).

DNA testing is not an all-male preserve. Female lineage can be traced using Mitochondria instead of the Y-Chromosome, but the patronymic nature of Irish surnames means that this form of testing is not useful in Irish genealogy. Please note that this particular DNA test is for men only! Don't blame us; Mother Nature makes the rules! Men who do not bear the Flannery surname, and women who bear the surname, may all participate vicariously by nominating a Flannery brother / uncle / cousin to be tested on their behalf.

DNA may be sampled in a number of ways. The easiest method is to take a minute sample of skin cells from the mouth by gently brushing the inside of the cheek with a small sterile brush. The process does not hurt. The test is self-administered using what looks like a travel toothbrush which is then popped into the post for analysis. A blood sample is not required!


DNA Fingerprint Testing

The familiar double-helix model of DNA was developed by Francis Crick & James Watson in 1953, and the DNA fingerprint was discovered by accident in 1985 by Alec Jeffreys.

The accuracy of the Y-Chromosome test, and reliability of the results, is directly related to the number of reference points (called markers) used in the analysis. The lowest useful resolution is 12 markers, and this was the world's first commercial DNA test developed by FamilyTreeDNA in the U.S.A. in March 2000. However, whilst the 12-markers test easily differentiates between Africans, Eastern Europeans etc., it lacks the fine resolution required to differentiate between the more recently arrived Western Europeans. Consequently, FamilyTreeDNA launched the 25-markers test in November 2001, and this has been adopted as the global standard (entry level). The 37-markers test was launched in December 2003, and this appears to be discriminating enough to differentiate individual family lines within a related group. The 67-markers test was launched in May 2006, but the additional markers will not be useful until mutation rates have been established for them.

It should be obvious at this point that Y-Chromosome testing was "emerging science" when we started our project in 2003. Since that date, numerous projects have been verified using conventional research run in parallel and there is now great confidence in the reliability of the test results.

The point in the Y-Chromosome where the marker is tested is called a DYS number. The test value assigned to each DYS is called an STR (Short Tandem Repeat).

The raw data table of 37 DYS STRs is called a haplotype. Exact or nearly exact matches of data establish the haplotype of the common ancestor. The next most important factor is the MRCA number (Most Recent Common Ancestor), which is the estimated number of generations to the occurance of the most recent common ancestor of two people.


Why Take The Test?

Our co-ordinated project of testing aims to achieve the following goals :-

  1. To identify three distinct DNA groups to verify the currently held theory that modern-day Flannerys and Flannellys descend from three distinct and unrelated septs (Ó Flannabhra of Connello barony in County Limerick, Ó Flannabhra of Tirawley barony in County Mayo, and Ó Flannghaile of Tireragh barony in County Sligo).

  2. To identify the sept(s) from which the Flannerys of North Clare, Galway, South Mayo and Kerry are descended.

  3. To identify the sept(s) from which the Flanarys of the Appalachians (and other significant migrant groups) are descended.

  4. To verify the extent to which the Flannellys have become absorbed by the Flannerys.

  5. To assist all participating clan members to identify their personal origins, both by connecting to other members and by connecting to one of the three distinct septs.

We are delighted to report that the project has proved to be very successful so far.


Does It Work?

The O'Gara Clan and the Kavanagh Clan have already embarked on Y-DNA projects, and the results to date have been very encouraging. We are grateful to Maura O'Gara-O'Riordan of the O'Gara Clan, and Fergus Kavanagh of the Kavanagh Clan, both serving directors of Clans of Ireland Ltd., for sharing their knowledge and bringing us up to speed on this exciting opportunity.

Check out the following websites for additional information on other successful surname DNA projects :-

  • Roper Surname Project

  • Mumma Surname Project

  • MacGregor Surname Project


    How Much Does It Cost?

    Technology has a price, of course. We have shopped around, and conclude that FamilyTreeDNA offer the best value. By proceeding as a registered group - as opposed to independent individuals - we can avail of a discounted group rate of approx. EUR 150 (US$190) per test (37-markers Y-DNA).


    Who Can Apply For The Test?

    Over eighty members have already taken the test. The first batch of test results has been filed, and subsequent test results (months, years or even decades hence) will be added to build up the database. The greater the number of test results, the greater the chance of achieving our stated objectives.

    Members who do not bear the Flannery surname, and female members who bear the surname, may all participate vicariously by nominating a male Flannery surname-bearing known relative to be tested on their behalf. We shall facilitate all members who wish to participate in this way.


    What About Privacy?

    All participants (and their DNA samples) are assigned code numbers, and the project co-ordinator is the only person able to match names to results.


    Are There Any Conditions?

    In order for the project to run smoothly, we have established a few basic ground rules :-

  • We initially adopted the 25-markers test, and do not encourage members to take just the 12-markers test. This is because the 12-markers test on its own does not provide sufficiently detailed information. The 37-markers test offers significant advantages by separating branches of families within each group, and we have now upgraded all of our tests. We are currently monitoring the 67-markers test, but have no immediate plans to upgrade to this level.

  • We bestow honorary life membership on all participants. This is because each and every test result helps us to form a vital core of information for present and future members.

  • All participating clan members must sign a waiver permitting their information to be shared within the clan. Please note that summary information shall be published, but personal information shall not be passed outside the clan.

  • All members who participate must pay their own test fee (approx. US$190) or any such revised test fee introduced by the testing agency in the future (inflation etc.). Payment must be sent directly to the testing agency, not to the clan.

  • Any results which might give rise to embarrassment shall be kept strictly confidential, and shall not even be shared within the clan.


    How To Proceed?

    The Flannery Clan Y-DNA Project commenced in Winter 2003 and is fully underway. Over eighty members have already taken the test, and we shall continue to admit additional participants as the years roll by.

    If you are interested in participating, then please register online at the testing agency's website (www.familytreedna.com). Alternatively, you may contact the Flannery Clan Y-DNA Project Co-ordinator (Lorcán J. O'Flannery) directly by either email or post (81 Woodford Drive, Clondalkin, Dublin 22, Ireland). Please be sure to give your full name and postal address. You will then be sent a waiver form to complete and return before your test kit is issued.

    Many of us regard this exercise as a unique opportunity to buttress previous research (based on primary and secondary sources) with definitive scientific evidence. We hope that the majority of our members recognise the importance of this project, and support the Flannery Clan by participating.


    Here Are The Results So Far

    It is still early days, but the first eighty or so results have been returned and analysed. Here are the preliminary conclusions :-

  • The results typically conform to Haplogroup R1b.

  • The sample size (80 returned results) has finally reached "critical mass" and is large enough for conventional Statistical Analysis. We have started to crunch the numbers and the preliminary analysis may be viewed by clicking HERE. Also, detailed Comparative Analysis of genetic distances has clearly identified two definite distinct Haplotypes and two further possible distinct Haplotypes, as follows:

    Group #1: Munster Flannery (38 results so far) =

    13 - 24 - 14 - 10 - 11 - 14 - 12 - 12 - 12 - 14 - 13 - 30
    16 - 9 - 10 - 11 - 11 - 26 - 16 - 19 - 29 - 15 - 15 - 17 - 17
    11 - 11 - 19 - 23 - 16 - 15 - 18 - 17 - 38 - 38 - 12 - 12

    Group #2: Connaught (probably Flannery but possibly Flannelly; specific to County Mayo and bordering areas so far) (28 results so far) =
    13 - 25 - 14 - 11 - 11 - 13 - 12 - 12 - 12 - 13 - 14 - 29
    17 - 9 - 10 - 11 - 11 - 25 - 15 - 18 - 29 - 15 - 16 - 16 - 17
    12 - 11 - 19 - 23 - 17 - 16 - 18 - 17 - 38 - 39 - 12 - 12

    Group #3: Connaught (Flannery; specific to Kiltullagh, County Galway to date) (4 results so far) =
    13 - 24 - 14 - 11 - 11 - 14 - 12 - 12 - 12 - 13 - 13 - 29
    17 - 9 - 10 - 11 - 11 - 25 - 15 - 19 - 29 - 15 - 15 - 16 - 17
    11 - 11 - 19 - 23 - 16 - 16 - 19 - 17 - 37 - 38 - 12 - 12

    Group #4: Connaught (probably Flannelly; specific to north Counties Mayo and Sligo to date) (5 results so far) =
    13 - 24 - 14 - 10 - 11 - 15 - 12 - 12 - 11 - 13 - 13 - 29
    17 - 9 - 10 - 11 - 11 - 25 - 15 - 19 - 31 - 15 - 15 - 16 - 16
    11 - 11 - 19 - 22 - 15 - 15 - 17 - 17 - 37 - 38 - 12 - 10

    where the red scores are deemed (by statistical analysis of our own test results) to be more prone to rapid mutation than the others, and the underlined scores are characteristic of the group.

  • The Appalachian Flanarys / Flannerys (descendants of Thomas Flanary 1722 - 1782) are part of the Munster Flannerys. This sub-group (11 results so far) typically conforms as follows:
    13 - 24 - 14 - 10 - 11 - 15 - 12 - 12 - 12 - 14 - 13 - 30
    16 - 9 - 10 - 11 - 11 - 26 - 16 - 19 - 29 - 15 - 15 - 17 - 17
    11 - 11 - 19 - 23 - 16 - 15 - 18 - 17 - 36 - 37 - 12 - 12

  • Click HERE to view the tabulated results grouped by haplotype; and click HERE to view the analysis and charts based on selected markers which highlight the distinct groups and families.


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